Advancing composite outcome measures: Insights on weighting components from OMERACT 2023
Authors' conclusion
The OMERACT 2023 workshop underscored the significance of a systematic approach to weighting components in composite outcome development. It highlighted the complexity of achieving consensus on the importance of domains and the role of incorporating the perspectives of patient research partners in this process.
Study context
- Population
- OMERACT 2023 workshop participants (OMERACT Composite Working Group), weighting the five domains of a composite outcome for OA flares
Methodological detailsOMERACT 2023 workshop, plenary sessions, breakout exercise, consensus discussions, Plenary introduced composite outcomes, a patient narrative, an OA flares composite and its five domains; breakout ranking and weighting of domains with group consensus discussions; closing plenary on weighting approaches incl. discrete choice and conjoint analysis (AAV working group)
- OMERACT 2023 workshop
- Plenary sessions
- Breakout exercise
- Consensus discussions
- Plenary introduced composite outcomes, a patient narrative, an OA flares composite and its five domains; breakout ranking and weighting of domains with group consensus discussions; closing plenary on weighting approaches incl. discrete choice and conjoint analysis (AAV working group)
Recommendations
As reported in the abstract
- Breakout exercise revealed the challenges in assigning relative importance to different domains, with variability in participant perspectives
- Consensus discussions highlighted diversity in weighting approaches, the need for appropriate methods to determine domain weights and the impact of weights on interpretation of composite scores
Original publication
Advancing composite outcome measures: Insights on weighting components from OMERACT 2023. Semin Arthritis Rheum. Published 30 June 2024. doi:10.
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