Active hand inflammation. Differing clinical and ultrasound patterns in patients with rheumatoid arthritis and psoriatic arthritis – A cross-sectional, multicenter study
Authors' conclusion
Synovial pannus was characteristic of RA, while paratenonitis was more common in PsA. SH≥2+PD correlated with erosive disease
Study context
- Population
- Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) patients with active hand inflammation; Ultrasound (US) of wrists and MCP joints focusing on extensor and flexor tendons192 (61.7%) women
- Participants
- 292 participants
- Exposure
- Seropositive RA vs seronegative RA vs PsA with active hand inflammation
- Seropositive RAn = 91
- Seronegative RAn = 79
- PsAn = 122
- Outcome
- Synovial hypertrophy (SH)≥2+PD
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
P ≤ 0.001
- Synovial hypertrophy (SH)≥2+PD overall
- 144 (49.3%)
Observational data: associations, not effects.
Further findings
Extensor paratenonitis — PsA vs Seropositive RA and seronegative RA
P ≤ 0.01
Factors associated with SH≥2+PD
- Erosive disease, OR [3.9-18], P≤0.001
- 8.4
- US global score, OR [1-1.1], P≤0.001
- 1.1
Factors associated with paratenonitis
- Number of swollen joints, OR [1-1.2], P≤0.001
- 1.1
- Joint ankylosis, OR [1.1-16.9], P≤0.05
- 4.3
Original publication
Active hand inflammation. Differing clinical and ultrasound patterns in patients with rheumatoid arthritis and psoriatic arthritis – A cross-sectional, multicenter study. Joint Bone Spine. Published 30 April 2025. doi:10. 1016/ j. jbspin. 2025. 105916
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