Lupus & antiphospholipid syndrome

Actigraphic and self-reported characterization of sleep in systemic lupus erythematosus patients

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

Compared with healthy controls, SLE patients showed worse sleep quality and greater perceived stress severity.

Study context

Population
SLE patients and age- and gender-matched healthy controls
Participants
40 vs 33
Exposure
SLE patients vs age- and gender-matched healthy controls
  • SLEn = 40
  • Controlsn = 33reference
Outcome
Sleep parameters by actigraphy (7 days), Pittsburgh Sleep Quality Index and Insomnia Severity Index
Methodological detailsage- and gender-matched healthy controls, 7-day actigraphic monitoring
  • Age- and gender-matched healthy controls
  • 7-day actigraphic monitoring

Main finding

As reported in the abstract

Sleep parameters, SLE vs controls
  • SLE: worse actigraphic sleep maintenance (sleep efficiency and wake after sleep onset)
  • SLE: higher total sleep time
  • SLE: higher perceived stress

Observational data: associations, not effects.

Further findings

Predictors of sleep parameters within SLE

Daily GC dose associated with impaired sleep maintenance without reduced sleep duration (normal sleep duration insomnia)
Perceived stress associated with short sleep duration insomnia

Original publication

Actigraphic and self-reported characterization of sleep in systemic lupus erythematosus patients. Rheumatology (Oxford). Published 11 July 2023. doi:10.1093/rheumatology/kead344

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