Accuracy of power Doppler ultrasonography in the diagnosis and monitoring of idiopathic inflammatory myopathies
Authors' conclusion
Our findings show that PDUS is a reliable diagnostic tool in the differential diagnosis between inflammatory and non-inflammatory myopathies.
Study context
- Population
- Patients with idiopathic inflammatory myopathies (IIM) evaluated in the Vasculitis and Myositis Clinic, Rheumatology Unit, University of Siena (median age 55 [IQR 45–66] years; 35 female)45 IIM patients
- Comparison
- Power Doppler ultrasonography (PDUS) score in IIM patients vs controls; and during follow-up
- IIMn = 45
- Outcome
- Diagnostic accuracy of PDUS score (IIM vs controls) and its usefulness during follow-up
Methodological detailsprospective, single-centre
- Prospective
- Single-centre
Performance
As reported in the abstract
Diagnostic accuracy (ROC) distinguishing IIM from controls
- Best cut-off ∑power Doppler (PD)
- 0.5
- Best cut-off ∑oedema
- 1.5
- Best cut-off ∑atrophy
- 0.5
- Best cut-off CRP (mg/dl)
- 0.22
- Logistic regression: ∑PD most influenced IIM diagnosis
- P = 0.017
- Logistic regression: ∑oedema most influenced IIM diagnosis
- P = 0.013
Further findings
Follow-up: ∑oedema lower than at T0 · T1 and T2
- T1 vs T0
- P = 0.0108
- T2 vs T0
- P = 0.0012
Follow-up: ∑PD lower than at T0 · T1 and T2
- T1 vs T0
- P = 0.0294
- T2 vs T0
- P = 0.0420
Follow-up: PGA lower than at baseline · T1 and T2
- T1 vs baseline
- P = 0.0349
- T2 vs baseline
- P = 0.0035
Original publication
Accuracy of power Doppler ultrasonography in the diagnosis and monitoring of idiopathic inflammatory myopathies. Rheumatology (Oxford). Published 22 June 2022. doi:10.
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