Fibromyalgia & musculoskeletal pain
A multicomponent physical activity home-based intervention for fibromyalgia patients: effects on clinical and skin biopsy features
Authors' conclusion
Physical activity could improve FM outcomes, with a possible beneficial impact on peripheral factors contributing to pain-related disability.
Study context
- Population
- Adult female fibromyalgia (FM) patients (51.5±11.88 years) on duloxetine and/or pregabalinall female
- Participants
- 34 patients
- Comparison
- 12-week supervised home-based multicomponent physical activity (PA) intervention vs generic aerobic exercise programme
- Experimentaln = 17
- Controln = 17reference
- Primary endpoint
- Pain perception, FM-related disability and IntraEpidermal Nerve Fibers Density (IENFD)
Methodological detailspilot, not pharmacological, home-based, Skin biopsy before the program and after 18 months
- Pilot
- Not pharmacological
- Home-based
- Skin biopsy before the program and after 18 months
Primary result
As reported in the abstract
18 months
- Significant improvement in FIQ in the supervised, regular PA group
- Significant improvement in epidermal fibers density at proximal and distal sites in the supervised, regular PA group
Original publication
A multicomponent physical activity home-based intervention for fibromyalgia patients: effects on clinical and skin biopsy features. Clin Exp Rheumatol. Published 20 June 2023. doi:10.
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