Fibromyalgia & musculoskeletal pain
Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials
Authors' conclusion
There is a low level of certainty surrounding the effectiveness of interventions for the management of sleep problems in people with fibromyalgia, but some forms of exercise training appear more likely to provide an improvement in sleep quality.
Study context
- Population
- Adults and children with FM and sleep problems65 studies in sleep-quality network meta-analyses (NMA)
- Participants
- 8,247 adults
- Comparison
- Pharmacologic and/or nonpharmacologic interventions vs placebo or sham treatments for FM-related sleep problems
- Outcome
- Sleep quality assessed using validated patient-reported outcome measures
Methodological detailsCochrane Risk-of-Bias tool, 168 studies included; databases searched November 2021
- Cochrane Risk-of-Bias tool
- 168 studies included; databases searched November 2021
Pooled result
As reported in the abstract
Sleep quality
Each group vs placebo or shamSMD (95% CrI)
Land-based aerobic exercise + flexibility training
−4.69(−8.14 to −1.28)
Aquatic-based aerobic exercise training
−2.63(−4.74 to −0.58)
Original publication
Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials. Arthritis Care Res (Hoboken). Published 26 March 2025. doi:10.
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