Rheumatoid arthritis

A global OMERACT ultrasound joint damage scoring system (GLODS) in rheumatoid arthritis

Ann Rheum DisPublished Reliability study

Authors' conclusion

Ultrasound is a reliable tool for evaluating bone erosions, cartilage change, and joint malalignment in the hand joints of patients with RA. These features can be reliably integrated into a global ultrasound score.

Study context

Population
Patients with rheumatoid arthritis (RA); MCP joints 1 to 5 of 7 patients scanned twice on the same day by 7 task force members
Participants
7 examiners
Outcome
Intraobserver and interobserver reliability (weighted kappa) of the GLODS and its components (bone erosions, cartilage change, joint malalignment)
Methodological detailsDelphi survey, web-based exercises, live patient-based exercise, Delphi agreement defined as ≥75% of grades 4-5 on a 1-5 Likert scale
  • Delphi survey
  • Web-based exercises
  • Live patient-based exercise
  • Delphi agreement defined as ≥75% of grades 4-5 on a 1-5 Likert scale

Main finding

As reported in the abstract

Reliability (weighted kappa)
Delphi agreement on statements (4 rounds)
9
Individual components, intra- and interobserver, web-based exercises
0.72-0.97
Individual components, intra- and interobserver, live exercises
0.68-0.89
Total GLODS, intraobserver (excellent)
0.92
Total GLODS, interobserver (good)
0.69

Observational data: associations, not effects.

Original publication

A global OMERACT ultrasound joint damage scoring system (GLODS) in rheumatoid arthritis. Ann Rheum Dis. Published 1 August 2026. doi:10.1016/j.ard.2026.07.004

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