Vasculitis & polymyalgia rheumatica

When it looks like Behçet’s syndrome but is something else: differential diagnosis of Behçet’s syndrome: a two-centre retrospective analysis

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

In a low disease prevalence setting, the straightforward application of the ICBD criteria may lead to overdiagnosis of BS. The differential diagnosis of BS is enormously broad.

Study context

Population
Patients with suspected Behçet's syndrome (BS) without confirmed BS, two referral centres in low prevalence regions
Participants
202 patients
Outcome
Differential diagnostic spectrum in patients with suspected BS
Methodological detailstwo-centre, referral centres for BS
  • Two-centre
  • Referral centres for BS

Main finding

As reported in the abstract

Differential diagnosis categories

Observational data: associations, not effects.

Further findings

Fulfilment of ICBD criteria despite not having BS

Patients fulfilling the ICBD criteria, 75/202
37.1%

HLA-B51 positivity

HLA-B51 positive, 55/132
41.7%

Original publication

When it looks like Behçet’s syndrome but is something else: differential diagnosis of Behçet’s syndrome: a two-centre retrospective analysis. Rheumatology (Oxford). Published 2 March 2023. doi:10.1093/rheumatology/kead101

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