Spondyloarthritis & psoriatic arthritis

What is the economic burden of delayed axial spondyloarthritis diagnosis in the UK?

Rheumatology (Oxford)Published Economic modelling study

Authors' conclusion

Delayed axial SpA diagnosis carries high costs for society due to productivity losses.

Study context

Population
Simulated, literature-defined mixed cohort (64% male) assumed to have axial SpA, age at symptom onset 26 years, UKsimulated cohort
Participants
1,000 participants
Outcome
Annual cost of delayed axial SpA diagnosis in the UK
Methodological detailsMarkov model, National Health Service (NHS) and societal perspectives, base case and probabilistic sensitivity analyses
  • Markov model
  • NHS and societal perspectives
  • Base case and probabilistic sensitivity analyses

Main finding

As reported in the abstract

Costs of delayed axial SpA diagnosis (mean time to diagnosis 8.5 years)
Cumulative cost of delayed diagnosis per person (95% CI 108 770-306 789)
£193 512
Share of costs from productivity losses
65.1%
Share of costs from out-of-pocket expenses
31.3%
Total annual UK cost, prevalence 0.3% (ASAS criteria)
£3.1 billion
Total annual UK cost, prevalence 1.2% (European Spondyloarthropathy Study Group criteria)
£12.5 billion

Original publication

What is the economic burden of delayed axial spondyloarthritis diagnosis in the UK? Rheumatology (Oxford). Published 25 April 2025. doi:10.1093/rheumatology/keaf226

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