Rheumatoid arthritis

What Affects Care Complexity in Rheumatoid Arthritis? An Integrative Review of Complexity Domains and Associated Patient and Health System Outcomes

J RheumatolPublished Integrative literature review

Authors' conclusion

We identified 12 domains of care complexity and 5 patient outcomes.

Study context

Population
Studies of people living with rheumatoid arthritis (RA) examining care complexity domains and patient, provider and health system outcomes181 articles included
Participants
181 participants
Outcome
RA-related care complexity domains and associated outcomes
Methodological detailsMEDLINE search, 2000 to present, constant comparison method, 9835 articles screened by the search
  • MEDLINE search, 2000 to present
  • Constant comparison method
  • 9835 articles screened by the search

Main finding

As reported in the abstract

Care complexity domains identified: comorbidity/multimorbidity and polypharmacy, overweight/obesity, substance use, mental health, chronic pain, difficult-to-treat RA, cognitive impairment, advanced age and/or frailty, race and ethnicity, socioeconomic considerations, social support/connectedness, healthcare access

12

Most common outcomes: impaired functional status, poor quality of life, elevated mortality risk, high disease activity and/or difficulty achieving remission, higher healthcare utilization

5

Original publication

What Affects Care Complexity in Rheumatoid Arthritis? An Integrative Review of Complexity Domains and Associated Patient and Health System Outcomes. J Rheumatol. Published 15 July 2026. doi:10.3899/jrheum.2026-0088

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