Lupus & antiphospholipid syndrome

Validating claims-based algorithms for a systemic lupus erythematosus diagnosis in Medicare data for informed use of the Lupus Index: a tool for geospatial research

Lupus Sci MedPublished Diagnostic accuracy study

Authors' conclusion

The findings of this study highlight the performance of specific ICD-10 code algorithms in identifying SLE and LN cases within Medicare data, providing a valuable tool for informing use of the Lupus Index.

Study context

Population
Prospective longitudinal cohort of patients with and without SLE from a South Carolina registry and rheumatology outpatient clinics; Medicare claims 2016–2018
Comparison
Claims-based ICD-10 algorithms vs ACR and SLICC criteria-based classification in a phenotyped cohort
Outcome
Performance of claims-based algorithms for identifying SLE and LN against ACR and SLICC criteria
Methodological detailsretrospective evaluation, rule-based ICD-10 algorithms, Medicare fee-for-service claims
  • Retrospective evaluation
  • Rule-based ICD-10 algorithms
  • Medicare fee-for-service claims

Performance

As reported in the abstract

  • Two ICD-10 codes for SLE, with or without a 30-day separation, showed the best overall performance
  • For lupus nephritis (LN), specific ICD-10 codes outperformed combinations of SLE and renal/proteinuria codes found in ICD-9

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Validating claims-based algorithms for a systemic lupus erythematosus diagnosis in Medicare data for informed use of the Lupus Index: a tool for geospatial research. Lupus Sci Med. Published 14 October 2024. doi:10.1136/lupus-2024-001329

Composed by AI from the published abstract and checked against it. How Briefs are made →

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