Vaccination coverage of influenza and pneumococcal vaccines in patients with rheumatic diseases: a systematic review and meta-analysis
Authors' conclusion
Influenza and pneumococcal vaccine coverage was still suboptimal in patients with rheumatic diseases.
Study context
- Population
- Patients with rheumatic diseases; studies from PubMed, Embase, Web of Science and Scopus51 studies
- Comparison
- RA vs SLE vs SpA vs PsA
- Outcome
- Coverage of influenza and pneumococcal vaccines
Methodological detailssensitivity analyses, subgroup analyses, meta-regression
- Sensitivity analyses
- Subgroup analyses
- Meta-regression
Pooled result
As reported in the abstract
Pooled influenza vaccination rate
Further pooled results
Pooled pneumococcal vaccination rate
Characteristics of vaccinated vs unvaccinated RA patients
- Vaccinated RA patients associated with older age and increased prevalence of comorbidities
Sources of heterogeneity
- Geographical location and use of DMARDs were two significant factors affecting heterogeneity
Vaccine education and reasons for non-vaccination
- Larger proportion received vaccine education from rheumatologists rather than general practitioners
- Two major reasons for non-vaccination: 'lack of awareness' and 'not offered by doctors'
Original publication
Vaccination coverage of influenza and pneumococcal vaccines in patients with rheumatic diseases: a systematic review and meta-analysis. Rheumatology (Oxford). Published 3 July 2026. doi:10. 1093/ rheumatology/ keag352
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