Use of prostaglandin and cyclophosphamide for pediatric lupus with digital gangrene: Back to safety before hitting the axe!
Study context
- Population
- Pediatric-onset systemic lupus erythematosus (SLE), both 16 years old, presenting with digital gangrene
- Participants
- 2 participants
- Outcome
- Digital gangrene after IV cyclophosphamide plus IV prostaglandin E1 infusions
Methodological detailstwo cases
- Two cases
Main finding
As reported in the abstract
- Both patients responded exceptionally, with resolution of gangrene and near-total preservation of toe functionality
Original publication
Use of prostaglandin and cyclophosphamide for pediatric lupus with digital gangrene: Back to safety before hitting the axe! Lupus. Published 24 October 2023. doi:10.
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