Vasculitis & polymyalgia rheumatica
Ultrasound centre frequency shifts as a novel approach for diagnosing giant cell arteritis
Authors' conclusion
This proof-of-principle study indicates that ultrasound CFS has the potential to detect GCA in temporal arteries.
Study context
- Population
- Temporal artery biopsy (TAB) specimens from subjects with suspected giant cell arteritis (GCA) (53 female, 15 male; mean age 73, range 52–87 years)53 female, 15 male
- Participants
- 68 participants
- Comparison
- Ultrasound centre frequency shift (CFS) in TAB-positive vs TAB-negative temporal arteries
- TAB-positiven = 25
- Outcome
- Ultrasound CFS discriminating GCA-affected from healthy temporal arteries
Methodological detailsproof-of-principle, ex vivo
- Proof-of-principle
- Ex vivo
Performance
As reported in the abstract
Ultrasound CFS decrease
- Ultrasound CFS decreased less in TAB-positive than in TAB-negative temporal arteries
- TAB-positive vs TAB-negative: P < 0.05
Original publication
Ultrasound centre frequency shifts as a novel approach for diagnosing giant cell arteritis. Scand J Rheumatol. Published 13 May 2022. doi:10.
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