Vasculitis & polymyalgia rheumatica
Ultrasonography in the assessment of disease activity in cranial and large-vessel giant cell arteritis: a prospective follow-up study
An erratum to this article was published (Rheumatology (Oxford), 1 Aug 2026 ↗)
Authors' conclusion
The OGUS is suggested as an outcome measurement for the assessment of treatment response in clinical trials.
Study context
- Population
- New-onset cranial and large-vessel GCA
- Participants
- 47 participants
- Outcome
- Sensitivity to change and discriminative abilities of vascular US scores in disease monitoring
Methodological detailsfollow-up study
- Follow-up study
Main finding
As reported in the abstract
US scores: sensitivity to change and discrimination · 8 weeks, 24 weeks and 15 months
- Baseline US positive
- 44/47
- Baseline US positive, temporal arteries (TA)
- 72%
- Baseline US positive, large-vessel (LV)
- 72%
- LVs responded poorly; new axillary US lesions despite clinical remission (patients)
- 6
- OGUS, TA halo count, Southend TA halo score, TA sum intima media complex (IMC) and TA mean IMC discriminate remission and relapse, AUC
- ≥0.8
Observational data: associations, not effects.
Original publication
Ultrasonography in the assessment of disease activity in cranial and large-vessel giant cell arteritis: a prospective follow-up study. Rheumatology (Oxford). Published 18 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →