Ultra-processed food intake and prevalence of osteoporosis in US adults aged 50 years and older: a cross-sectional analysis
Main finding · Osteopenia or osteoporosisResult — go to the resultOdds ratio 1.52 95% CI 1.28–1.79Authors' conclusion
These findings indicate an association between osteoporosis and osteopenia and the intake of UPF as a proportion of total daily energy.
Study context
- Population
- US adults aged 50 years and older, NHANES
- Exposure
- Highest vs lowest quintile of ultra-processed foods (UPF) intake as a proportion of daily energy intake
- Outcome
- Prevalence of osteopenia or osteoporosis
Methodological detailsregression analysis adjusted for covariates, four NHANES cycles, 24-h dietary recall
- Regression analysis adjusted for covariates
- Four NHANES cycles
- 24-h dietary recall
Main finding
Osteopenia or osteoporosis
Odds ratio
1.52
95% CI 1.28–1.79
Highest quintilevs Lowest quintile
OR 1.52 (95% CI 1.28–1.79)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalence of osteopenia and osteoporosis by sex
- Osteopenia, women
- 50.5%
- Osteopenia, men
- 28.0%
- Osteoporosis, women
- 8.2%
- Osteoporosis, men
- 1.8%
Self-reported prior hip, wrist or spine fracture in women, per percentage increase in UPF intake
- Increase in odds per percentage increase in UPF proportion
- 1.9% (95% CI 1.003, 1.035)
Fracture in men
- Increased risk of fracture not observed among men
Original publication
Ultra-processed food intake and prevalence of osteoporosis in US adults aged 50 years and older: a cross-sectional analysis. Osteoporos Int. Published 28 January 2025. doi:10.
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