Plant-Based Diets and Risk of Hip Fracture in Postmenopausal Women
Authors' conclusion
Findings of this cohort study indicated that long-term adherence to healthful or unhealthful plant-based diets as assessed by hPDI and uPDI scores was not associated with hip fracture risk.
Study context
- Population
- Postmenopausal women in the US Nurses' Health Study, 1984–2014 (mean age 54.92 years; 100% White)2,038 hip fractures
- Participants
- 70,285 women
- Exposure
- Highest vs lowest quintile of hPDI and of uPDI
- Outcome
- Hip fracture (self-reported), by long-term diet adherence
- Follow-up
- Up to 30 years
Methodological detailsCox proportional hazards regression with time-varying covariates
- Cox proportional hazards regression with time-varying covariates
Main finding
As reported in the abstract
Hip fracture, long-term diet adherence
Hazard ratio (95% CI)
hPDI highest quintilevs hPDI lowest quintile
0.97(0.83–1.14)
uPDI highest quintilevs uPDI lowest quintile
1.02(0.87–1.20)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Hip fracture, recent dietary intakehPDI highest quintilevs hPDI lowest quintile21% lower risk | 0.79 (0.68–0.92) | P = 0.02 for trend | |
| Hip fracture, recent dietary intakeuPDI highest quintilevs uPDI lowest quintile28% higher risk | 1.28 (1.09–1.51) | P = 0.008 for trend | |
| 0.512Hazard ratio (log scale) |
Original publication
Plant-Based Diets and Risk of Hip Fracture in Postmenopausal Women. JAMA Netw Open. Published 5 February 2024. doi:10.
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