Metaphyseal comminution in distal radius fractures: a predictor of secondary fragility fractures and the role of osteoporosis treatment
Main finding · Secondary fracturesResult — go to the resultHazard ratio 5.2 95% CI 1.4–10.7Authors' conclusion
Metaphyseal comminution in patient with DRFs significantly elevated secondary fracture risk; combination osteoporosis therapy might mitigate this risk.
Study context
- Population
- Patients aged ≥ 50 years who underwent distal radius fracture (DRF) surgery at a single institution, July 2018 to December 2022
- Participants
- 134 patients
- Exposure
- DRF with vs without metaphyseal comminution
- Comminutionn = 45
- Non-comminutionn = 89reference
- Outcome
- Secondary fracture incidence
Methodological detailssingle institution, multivariate Cox model
- Single institution
- Multivariate Cox model
Main finding
Secondary fractures
Hazard ratio
5.2
95% CI 1.4–10.7
P = 0.004
By group
Comminutionvs Non-comminution
HR 5.2 (95% CI 1.4–10.7); P = 0.004
As reported in the abstract
Observational data: associations, not effects.
Further findings
Secondary fracture rate by osteoporosis treatment
P = 0.046
- Secondary fracture rate by osteoporosis treatment: combination therapy: active vitamin D plus bisphosphonates or anabolic agents
Original publication
Metaphyseal comminution in distal radius fractures: a predictor of secondary fragility fractures and the role of osteoporosis treatment. Osteoporos Int. Published 28 January 2025. doi:10.
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