Clinical role and timing of osteoporosis evaluation and treatment after distal radius fracture: a scoping review
Authors' conclusion
A fragility DRF warrants prompt secondary prevention, assessment for secondary causes, and timely indicated treatment. DXA and FRAX can inform individualized decisions but should not delay indicated care. Observational associations do not establish a causal treatment effect; optimal timing and benefit in normal-BMD patients remain unresolved.
Study context
- Population
- Adults aged ≥50 years with distal radius fracture (DRF) or wrist fragility fracturereports (2008–2026) · BMD-based risk and selection 103 · care gap 65 · prognosis 40 · treatment 42
- Participants
- 250 adults
- Outcome
- DXA testing and treatment-initiation rates (median)
Methodological detailsJBI-guided, reported per PRISMA-ScR, prospectively registered on OSF, dual large language model screening, independently audited in duplicate by two authors, source-verified charting, synthesized descriptively without pooling
- JBI-guided
- Reported per PRISMA-ScR
- Prospectively registered on OSF
- Dual large language model screening, independently audited in duplicate by two authors
- Source-verified charting
- Synthesized descriptively without pooling
Main finding
As reported in the abstract
Median DXA testing rate
26%
Median treatment-initiation rate
22%
Further findings
Treatment or structured care and fracture outcomes
- Observational reports linking treatment or structured care to fracture outcomes
- Eleven
- A separate economic model projected outcomes
- Estimates were heterogeneous and not pooled.
Early versus delayed treatment initiation after DRF
- No included study directly compared early versus delayed treatment initiation after DRF with subsequent fracture as the outcome
Normal BMD
- Reports focused on normal BMD
- Six
- None estimated subgroup-specific fracture outcomes
Original publication
Clinical role and timing of osteoporosis evaluation and treatment after distal radius fracture: a scoping review. Osteoporos Int. Published 27 October 2026. doi:10.
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