Spondyloarthritis & psoriatic arthritis
Tuft resorption in patients with psoriatic arthritis
Authors' conclusion
TR is a common radiographic feature of PsA. It is associated with more severe disease, including peripheral and axial radiographic damage.
Study context
- Population
- Patients with psoriatic arthritis (PsA) followed at a prospective observational cohort
- Participants
- 1,303 patients
- Outcome
- Prevalence of tuft resorption (resorptive changes in the terminal tufts of the fingers or toes)
Methodological detailsprospective observational cohort, generalized estimating equations, multivariate Cox regression
- Prospective observational cohort
- Generalized estimating equations
- Multivariate Cox regression
Main finding
As reported in the abstract
Prevalence of tuft resorption
Patients with tuft resorption (TR)
526
40.4 %
Developed TR during follow-up, of those with TR
181
34.4 %
Observational data: associations, not effects.
Further findings
Features cross-sectionally associated with TR
- Older age, OR
- 1.49, p < 0.01
- Longer PsA duration, OR
- 1.03, p < 0.01
- Higher radiographic damaged joint count, OR
- 1.02, p = 0.04
- Axial disease, OR
- 1.73, p < 0.01
- Number of systemic disease-modifying anti-rheumatic drugs (DMARDs) used, OR
- 1.27, p < 0.01
Factors associated with development of TR
- Male sex, HR
- 1.54, p = 0.01
- Vertebral osteopenia, HR
- 1.39, p = 0.02
- NSAID use, HR
- 1.43, p = 0.03
- b/tsDMARD use (protective, not significant at the 5 % level), HR
- 0.70, p = 0.05
Original publication
Tuft resorption in patients with psoriatic arthritis. Semin Arthritis Rheum. Published 7 March 2025. doi:10.
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