Time trends in the burden of autoimmune diseases across the BRICS: an age–period–cohort analysis for the GBD 2019
Authors' conclusion
And we found that the age effect of various autoimmune diseases is heavily influenced by population ageing.
Study context
- Population
- BRICS countries (Brazil, Russia, India, China, South Africa), 1990–2019: Rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis and psoriasis
- Outcome
- Long-term trends in prevalence and DALY rate by age, period and cohort
- Follow-up
- 1990 to 2019
Methodological detailsJoinpoint regression, age-period-cohort model
- Joinpoint regression
- Age-period-cohort model
Main finding
As reported in the abstract
Russian ASPR of multiple sclerosis, average annual percent change
−0.5%
95% CI −0.6 to −0.5
Most increased ASPR of multiple sclerosis in Brazil
2009-2014
RRs of DALYs due to RA, from 20 to 24 to 65 to 69 age group, five countries (times)
7.98, 16.07, 5.98, 3.19, 9.13
Observational data: associations, not effects.
Original publication
Time trends in the burden of autoimmune diseases across the BRICS: an age–period–cohort analysis for the GBD 2019. RMD Open. Published 6 December 2023. doi:10.
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