The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development
Authors' conclusion
Specific symptoms can provide useful information to estimate a person's RA risk.
Study context
- Population
- At-risk individuals for RA (ACPA and/or RF positive, or relevant symptoms with or without RA antibodies) from cohorts in the Netherlands, UK, Sweden and Switzerlandmean age 50 years, 67% female
- Participants
- 214 individuals
- Outcome
- Clinical arthritis development
- Follow-up
- ≥ 24 months or until clinical arthritis development
Methodological detailsmulticentre (four cohorts), stepwise forward selection prediction models
- Multicentre (four cohorts)
- Stepwise forward selection prediction models
Main finding
As reported in the abstract
Symptoms predicting arthritis development
Clinical arthritis development (n = 58), median time 7 months
27%
Observational data: associations, not effects.
Original publication
The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development. Scand J Rheumatol. Published 29 September 2022. doi:10.
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