The role of magnetic resonance imaging in the diagnostic work-out of myopathies: differential diagnosis between inflammatory myopathies and muscular dystrophies
Authors' conclusion
A different distribution of muscular involvement between IIM and MD has been identified.
Study context
- Population
- Patients with idiopathic inflammatory myopathies (IIM) or MD undergoing muscular magnetic resonance imaging (MRI)
- Participants
- 91 vs 43
- Comparison
- IIM vs MD
- IIMn = 91
- MDn = 43reference
- Outcome
- Muscular MRI findings (oedema, atrophy, intramuscular adipose changes)
Methodological detailsstandardised MRI protocol, composite score for each MRI item
- Standardised MRI protocol
- Composite score for each MRI item
Performance
As reported in the abstract
- Probability of IIM increased with higher oedema score and decreased with higher atrophy and intramuscular adipose infiltration/substitution scores
- IIM vs MD: P < 0.001
- IIM vs MD: P = 0.044
- MD vs IIM: P < 0.05
- MD vs IIM: P < 0.001
Original publication
The role of magnetic resonance imaging in the diagnostic work-out of myopathies: differential diagnosis between inflammatory myopathies and muscular dystrophies. Clin Exp Rheumatol. Published 31 July 2022. doi:10.
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