Across rheumatic diseases

The link between traumatic stress and autoimmune rheumatic diseases: A systematic scoping review

Semin Arthritis RheumPublished Systematic scoping review

Authors' conclusion

This scoping review reveals a notable dearth in research on the impact of traumatic stress, such as ACEs, PTSD, and major life events, on ARDs, especially on rare diseases, yet underscores a significant association between trauma and ARD severity or incidence.

Study context

Population
Studies on the association between self-reported traumatic stress (adverse childhood experiences (ACEs), Post-traumatic Stress Disorder (PTSD), major life stressors) and autoimmune rheumatic diseases; Embase, Medline, Web of Science searched 15th December 2023; English only21 studies
Outcome
Traumatic stress and ARDs
Methodological detailsobservational studies (cohort, case-control, cross-sectional), two authors independently assessed inclusion and extracted data
  • Observational studies (cohort, case-control, cross-sectional)
  • Two authors independently assessed inclusion and extracted data

Main finding

As reported in the abstract

Studies included, primarily from high-income countries (especially USA), 2000 to 2023
21

Observational data: associations, not effects.

Original publication

The link between traumatic stress and autoimmune rheumatic diseases: A systematic scoping review. Semin Arthritis Rheum. Published 21 September 2024. doi:10.1016/j.semarthrit.2024.152558

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