The link between traumatic stress and autoimmune rheumatic diseases: A systematic scoping review
Authors' conclusion
This scoping review reveals a notable dearth in research on the impact of traumatic stress, such as ACEs, PTSD, and major life events, on ARDs, especially on rare diseases, yet underscores a significant association between trauma and ARD severity or incidence.
Study context
- Population
- Studies on the association between self-reported traumatic stress (adverse childhood experiences (ACEs), Post-traumatic Stress Disorder (PTSD), major life stressors) and autoimmune rheumatic diseases; Embase, Medline, Web of Science searched 15th December 2023; English only21 studies
- Outcome
- Traumatic stress and ARDs
Methodological detailsobservational studies (cohort, case-control, cross-sectional), two authors independently assessed inclusion and extracted data
- Observational studies (cohort, case-control, cross-sectional)
- Two authors independently assessed inclusion and extracted data
Main finding
As reported in the abstract
- Studies included, primarily from high-income countries (especially USA), 2000 to 2023
- 21
Observational data: associations, not effects.
Original publication
The link between traumatic stress and autoimmune rheumatic diseases: A systematic scoping review. Semin Arthritis Rheum. Published 21 September 2024. doi:10. 1016/ j. semarthrit. 2024. 152558
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