Across rheumatic diseases

Large language models in rheumatology-centered research: A scoping review of model openness and reporting practices

Semin Arthritis RheumPublished Scoping review

Authors' conclusion

LLM-based rheumatology research largely depends on closed models with inconsistent reporting of reproducibility-critical details and minimal code sharing.

Study context

Population
English-language peer-reviewed original rheumatology research using large language models (LLMs), PubMed/MEDLINE, 1 November 2022 to 23 January 2026185 records screened
Participants
63 studies
Outcome
Model openness and reporting practices
Methodological detailsdual independent screening, LLM-assisted data extraction verified by authors
  • Dual independent screening
  • LLM-assisted data extraction verified by authors

Main finding

As reported in the abstract

Closed/proprietary LLMs
n = 50/63; 79.37%
Exclusive use of open-weight models
n = 4/63; 6.35%
Hybrid use
n = 9/63; 14.29%
OpenAI models
n = 55/63; 87.30%
Interaction language not reported
n = 42/63; 66.67%
Access mode reported
n = 19/63; 30.16%
Output generation date reported
n = 33/63; 52.38%
Prompts shared
n = 48/63; 76.19%
Code publicly available
n = 4/63; 6.35%
Data publicly available
n = 13/63; 20.63%

Further findings

Study focus

Research-focused
n = 26/63; 41.27%
Education-focused
n = 20/63; 31.75%

Original publication

Large language models in rheumatology-centered research: A scoping review of model openness and reporting practices. Semin Arthritis Rheum. Published 9 May 2026. doi:10.1016/j.semarthrit.2026.152994

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