Spondyloarthritis & psoriatic arthritis
The likelihood of joint inflammation recurrence in previously affected joints during psoriatic arthritis disease course
Main finding · Future joint swellingResult — go to the resultOdds ratio 2.88 95% CI 2.61–3.18Authors' conclusion
This study identified a strong association between baseline joint swelling and subsequent swelling episodes in patients with PsA.
Study context
- Population
- Patients with PsA followed at the Tel Aviv Medical Center Rheumatology Institute; 44% male, mean age 48 y/o (SD 15), mean disease duration 1 yearjoints assessed in 492 patients
- Participants
- 33,456 patients
- Exposure
- Joints swollen at baseline vs joints not swollen at baseline
- Swollen at baselinen = 1,402
- Outcome
- Recurrence of joint inflammation (swelling, SJC68) in previously affected joints during follow-up
Methodological detailsreal-world data, single-centre, mixed-effects logistic regression adjusted for joint location and follow-up visit, Median 6 (IQR 4-9) follow-up visits
- Real-world data
- Single-centre
- Mixed-effects logistic regression adjusted for joint location and follow-up visit
- Median 6 (IQR 4-9) follow-up visits
Main finding
Future joint swelling · during follow-up
Odds ratio
2.88
95% CI 2.61–3.18
Events by group
Swollen at baseline
36.7%
514 of 1402
Swollen at baselinevs Not swollen at baseline
OR 2.88 (95% CI 2.61–3.18)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Patients with at least 1 swollen joint at baseline
- Patients with ≥1 swollen joint
- 420 (85%)
- Median SJC68
- 2 (1-5)
Original publication
The likelihood of joint inflammation recurrence in previously affected joints during psoriatic arthritis disease course. Ann Rheum Dis. Published 26 September 2025. doi:10. 1016/ j. ard. 2025. 08. 020
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