Autoinflammatory & rare systemic diseases
The landscape of innate and adaptive immune cell subsets in patients with adult-onset Still’s disease
Authors' conclusion
Our findings showed the activation of the innate and adaptive immune system in AOSD.
Study context
- Population
- Patients with active adult-onset Still's diseaseactive Adult-onset Still's disease (AOSD)
- Participants
- 29 patients
- Comparison
- Active AOSD vs healthy controls
- AOSDn = 29
- Outcome
- Peripheral immune cell composition and serum inflammatory protein levels
Methodological detailsflow cytometry, antibody chips
- Flow cytometry
- Antibody chips
Main finding
As reported in the abstract
- Serum proteins elevated (cytokine-cytokine receptor interaction, inflammatory response, MAPK cascade regulation)
- 40
Original publication
The landscape of innate and adaptive immune cell subsets in patients with adult-onset Still’s disease. Rheumatology (Oxford). Published 26 September 2023. doi:10.
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