Autoinflammatory & rare systemic diseases
Management of adult-onset Still's disease: evidence- and consensus-based recommendations by experts
Methodological detailsDelphi panel, three rounds, consensus threshold 80%, targeted literature searches
- Delphi panel
- Three rounds
- Consensus threshold 80%
- Targeted literature searches
Recommendations
As issued by the authors
Consensus on 29 statements: diagnosis and diagnostic tests, definition of response and remission, therapy, use of MTX and tapering of treatment
Reduce use of GC to avoid side effects
Biologics preferred over conventional treatment
IL-1 and IL-6 blocking agents considered important in Adult-onset Still's disease (AOSD) treatment
Original publication
Management of adult-onset Still's disease: evidence- and consensus-based recommendations by experts. Rheumatology (Oxford). Published 5 September 2023. doi:10.
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