The incidence of Kawasaki disease using hospital admissions data for England 2006–2021
Authors' conclusion
Incidence rates of kDa derived from hospital admission data in England were higher than in studies relying on clinician reporting.
Study context
- Population
- Children under 16 with Kawasaki disease (ICD-10 M303) in hospital admissions data, England, 1 April 2006–31 March 2021cases of Kawasaki Disease (kDa)
- Participants
- 5,908 participants
- Exposure
- Age <5 years vs Age 5-9 vs Age 10-15
- Outcome
- Incidence of Kawasaki disease
Methodological detailshospital episode statistics, Poisson regression, national population-based, 83 diagnoses validated against hospital medical records: >97% accuracy
- Hospital episode statistics
- Poisson regression
- National population-based
- 83 diagnoses validated against hospital medical records: >97% accuracy
Main finding
As reported in the abstract
Incidence of kDa by age
Aged <5 years
8.9
95% CI 8.6–9.2 · /100 000 person-years
Aged 5-9
2.4
95% CI 2.3–2.6 · /100 000 person-years
Aged 10-15
0.6
95% CI 0.6–0.7
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted IRR (CI) | |
|---|---|---|
| Incidence by ethnicity (vs White)Asianvs White | 2.1 (2.0–2.2) | |
| Incidence by ethnicity (vs White)Blackvs White | 3.0 (2.8–3.3) | |
| Incidence by ethnicity (vs White)Other ethnicitiesvs White | 4.5 (4.2–4.8) | |
| Incidence by deprivation (IMD quintile)Least deprived IMD quintilevs Most deprived quintile | 0.81 (0.77–0.84) | |
| 0.20.5125Adjusted incidence rate ratio (log scale) |
Sex
- Male : female ratio
- 1.5 : 1
Original publication
The incidence of Kawasaki disease using hospital admissions data for England 2006–2021. Rheumatology (Oxford). Published 30 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →