Spondyloarthritis & psoriatic arthritis
The epidemiology of psoriatic arthritis in the UK: a health intelligence analysis of UK Primary Care Electronic Health Records 1991–2020
Authors' conclusion
The prevalence and incidence of PsA recorded in primary care has increased over the last three decades.
Study context
- Population
- UK primary care (Clinical Practice Research Datalink (CPRD)), 1 January 1991 to 31 December 2020
- Participants
- 26,293 recorded psoriatic arthritis (PsA) cases
- Exposure
- Definite PsA vs Probable PsA
- Outcome
- Standardized annual prevalence and incidence of PsA
- Follow-up
- 1991 to 2020
Methodological detailsBayesian multilevel regression with post-stratification, CPRD primary care electronic health records
- Bayesian multilevel regression with post-stratification
- CPRD primary care electronic health records
Main finding
As reported in the abstract
Standardized prevalence and incidence of PsA, 1991 to 2020
Standardized prevalence, 1991 to 2020 (twelve-fold increase)
0.03-0.37
Standardized incidence per 100 000 person years, 1991
8.97
Standardized incidence per 100 000 person years, 2020 (almost 2-fold increase)
15.08
Observational data: associations, not effects.
Further findings
Rates by sex, socioeconomic status, age and region
- Rates similar between the sexes and across socioeconomic status over time
- Rates strongly associated with age
- Rates consistently highest in Northern Ireland
Original publication
The epidemiology of psoriatic arthritis in the UK: a health intelligence analysis of UK Primary Care Electronic Health Records 1991–2020. Rheumatology (Oxford). Published 2 November 2023. doi:10. 1093/ rheumatology/ kead586
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