The diagnostic value of MRI-based vertebral bone quality score for osteoporosis or osteopenia in patients undergoing lumbar surgery: a meta-analysis
Authors' conclusion
The MRI-based VBQ score could provide useful information for identifying patients with low bone mass who need further evaluation.
Study context
- Population
- Patients with lumbar disease undergoing lumbar surgery (mean age 66.4 years; 72.5% female)
- Participants
- 2,815 patients17 studies
- Comparison
- MRI-based Vertebral Bone Quality (VBQ) score for osteoporosis or osteopenia
- Outcome
- Diagnostic accuracy of the VBQ score for osteoporosis/osteopenia (pooled sensitivity, specificity, summary ROC)
Methodological detailsPRISMA, QUADAS-2 quality assessment, meta-regression, Quality of included studies relatively high (QUADAS-2)
- PRISMA
- QUADAS-2 quality assessment
- Meta-regression
- Quality of included studies relatively high (QUADAS-2)
Pooled result
As reported in the abstract
Diagnostic accuracy of VBQ score
| Strategy | AUC | Pooled sensitivity | Pooled specificity |
|---|---|---|---|
| VBQ score (osteoporosis) | 0.81 | 0.76 | 0.74 |
| VBQ score (osteopenia) | 0.76 | 0.78 | 0.58 |
AUC
VBQ score (osteoporosis)0.81
VBQ score (osteopenia)0.76
Pooled sensitivity
VBQ score (osteoporosis)0.76
VBQ score (osteopenia)0.78
Pooled specificity
VBQ score (osteoporosis)0.74
VBQ score (osteopenia)0.58
Further pooled results
- Significantly higher VBQ score in the osteoporosis/osteopenia group vs control group
Original publication
The diagnostic value of MRI-based vertebral bone quality score for osteoporosis or osteopenia in patients undergoing lumbar surgery: a meta-analysis. Osteoporos Int. Published 1 August 2024. doi:10.
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