Osteoporosis & bone health

Opportunistic use of lumbar computed tomography and magnetic resonance imaging for osteoporosis screening

Osteoporos IntPublished Diagnostic accuracy study

Authors' conclusion

Opportunistic use of CT and MRI can simply distinguish patients with OP, which are expected to be potential alternatives to T-score for the osteoporosis screening.

Study context

Population
Lumbar spine surgery patients who received lumbar quantitative CT (QCT) and magnetic resonance imaging (MRI)
Participants
109 patients
Comparison
Computed tomography (CT)-based Hounsfield unit (HU) value vs MRI-based vertebral bone quality (VBQ) score for identifying osteoporosis, against QCT
Outcome
Diagnostic performance (AUC) for OP, based on QCT results
Methodological detailsretrospective
  • Retrospective

Performance

As reported in the abstract

Diagnostic performance for OP (AUC)
Test or modelAUCDiagnostic threshold
HU value0.95997.06
VBQ score0.8803.08

AUC

HU value0.959
VBQ score0.880

Diagnostic threshold

HU value97.06
VBQ score3.08

Further findings

HU value and VBQ score in osteoporosis (OP) vs non-OP patients

HU value significantly lower in the OP group
VBQ score significantly higher in the OP group

Original publication

Opportunistic use of lumbar computed tomography and magnetic resonance imaging for osteoporosis screening. Osteoporos Int. Published 28 June 2024. doi:10.1007/s00198-024-07164-8

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