Fibromyalgia & musculoskeletal pain
The concomitant diagnosis of fibromyalgia and connective tissue disorders: A systematic review
Authors' conclusion
There may be overlapping symptomatology and diagnostic prevalence of FMS and hEDS/HSD/GJH.
Study context
- Population
- Adults screened for hypermobile Ehlers-Danlos Syndrome (hEDS)/Hypermobility Spectrum disorders (HSD)/Generalized Joint Hypermobility (GJH) and fibromyalgia syndrome (FMS); paediatric studies excluded11 studies
- Comparison
- Concomitant diagnosis of FMS with hEDS/HSD/GJH
- Outcome
- Prevalence of concomitant diagnosis of FMS and hEDS/HSD/GJH, and shared symptomatic manifestations
Methodological detailsobservational studies (case-control or single group), MEDLINE search, prospectively registered
- Observational studies (case-control or single group)
- MEDLINE search
- Prospectively registered
Pooled result
As reported in the abstract
Prevalence of concomitant diagnosis
Concomitant hEDS/HSD and FMS
68%-88.9%
Concomitant GJH and FMS
8.0 to 64.2%
Further pooled results
Shared features, hEDS/HSD vs FMS
- Prevalence and severity similar between hEDS/HSD and FMS: joint pain, joint swelling, muscle weakness, neurological problems, MPI-activity, dysautonomia and total autonomic symptoms burden, function, and quality of life
Shared features, GJH vs FMS
- Shared: mean pain level, tender points count, total myalgia score and psychological impact
Original publication
The concomitant diagnosis of fibromyalgia and connective tissue disorders: A systematic review. Semin Arthritis Rheum. Published 17 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →