Spondyloarthritis & psoriatic arthritis
The association between cigarette smoking and radiographic progression in Psoriatic Arthritis
Authors' conclusion
Cigarette smoking does not appear to be significantly associated with the progression of joint damage in PsA.
Study context
- Population
- Patients with psoriatic arthritis (PsA) from an observational cohort (54.9% male; mean age 44.9 years)308 missing smoking data
- Participants
- 1,736 patients
- Exposure
- Current or past smoking vs non-smoking
- Non-smokersn = 906reference
- Past smokersn = 211
- Current smokersn = 311
- Outcome
- Change in radiographic joint damage (modified Steinbrocker score)
Methodological detailsobservational cohort, linear mixed models
- Observational cohort
- Linear mixed models
Main finding
As reported in the abstract
Change in modified Steinbrocker score (multivariable linear mixed model)
Estimate
−0.18
95% CI −0.94 to 0.58
current
Estimate
−0.67
95% CI −1.51 to 0.17
past
Observational data: associations, not effects.
Further findings
Factors associated with increased joint damage (multivariable model)
- Longer duration between first and last radiographs, higher baseline modified Steinbrocker score and csDMARD use significantly associated with increased joint damage
Original publication
The association between cigarette smoking and radiographic progression in Psoriatic Arthritis. Semin Arthritis Rheum. Published 2 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →