Systemic juvenile idiopathic arthritis: Are there any predictors of disease course?
Main findingResult — go to the resultOdds ratio 12.68 95% CI 2.69–59.90Authors' conclusion
Polyarthritis at presentation was associated with increased risk of a non-monophasic disease course in this study population.
Study context
- Population
- Children with systemic juvenile idiopathic arthritis (sJIA) over 18 years; median age at diagnosis 8 yearsmedian follow-up 6 years
- Participants
- 80 children
- Exposure
- Clinical and laboratory features at presentation as predictors of non-monophasic vs monophasic sJIA course
- Monophasicn = 34
- Polycyclicn = 8
- Persistentn = 38
- Outcome
- Predictors of non-monophasic (polycyclic or persistent) disease course
Methodological detailsretrospective observational, logistic regression adjusted for age, gender and year of diagnosis
- Retrospective observational
- Logistic regression adjusted for age, gender and year of diagnosis
Main finding
As reported in the abstract
Odds ratio
12.68
95% CI 2.69–59.90
P = 0.001
Clinical and laboratory features at presentation as predictors of non-monophasicvs monophasic sJIA course
OR 12.68 (95% CI 2.69–59.90); P = 0.001
Observational data: associations, not effects.
Further findings
Disease course distribution
Presenting features
- Rash (most common presenting feature)
- 83.8%
- Arthritis
- 66.3%
- Macrophage activation syndrome (MAS)
- 18.8%
Original publication
Systemic juvenile idiopathic arthritis: Are there any predictors of disease course? Rheumatology (Oxford). Published 11 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →