Systematic review and meta-analysis of preoperative predictors for early mortality following hip fracture surgery
Authors' conclusion
This review found relevant preoperative predictors which could be used to identify patients who are at high risk of 30-day mortality following hip fracture surgery.
Study context
- Population
- Patients undergoing hip fracture surgery; cohort studies of independent preoperative predictors of mortality identified through Scopus and PubMed
- Participants
- 462,699 patients33 cohort studies
- Outcome
- Predictors for 30-day mortality
- Follow-up
- 30 days
Methodological detailsrandom-effects meta-analysis, GRADE assessment of evidence certainty, narrative synthesis of secondary outcomes
- Random-effects meta-analysis
- GRADE assessment of evidence certainty
- Narrative synthesis of secondary outcomes
Pooled result
As reported in the abstract
Predictors of 30-day mortality (high-quality evidence)
- Age per year, OR
- 1.06 (95% CI 1.04-1.07)
- ASA score ≥ 3, OR
- 2.69 (95% CI 2.12-3.42)
- Male gender, OR
- 2.00 (95% CI 1.85-2.18)
- Institutional residence, OR
- 1.81 (95% CI 1.31-2.49)
- Metastatic cancer, OR
- 2.83 (95% CI 2.58-3.10)
Further pooled results
Moderate-quality evidence predictors of 30-day mortality
- Chronic renal failure, dementia, diabetes, low haemoglobin, heart failures and a history of any malignancy
Non-metastatic cancer · 30 days
- Weak evidence as predictor of 30-day mortality
Original publication
Systematic review and meta-analysis of preoperative predictors for early mortality following hip fracture surgery. Osteoporos Int. Published 24 November 2023. doi:10. 1007/ s00198-023-06942-0
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