Management of bone health in cancer survivorship: a systematic review of clinical guidelines
Authors' conclusion
Findings highlight variations in guideline quality, with many lacking holistic, multidisciplinary recommendations for bone health management.
Study context
- Population
- Clinical guidelines on bone health (fracture and osteoporosis risk) for people with cancer; PubMed, EMBASE, CINAHL and Scopus
- Participants
- 65 guidelines
- Outcome
- Guideline recommendation domains
Methodological detailsAGREE II quality appraisal, independent data extraction by multiple authors
- AGREE II quality appraisal
- Independent data extraction by multiple authors
Pooled result
As reported in the abstract
- Recommendations related to lifestyle (most commonly vitamin D and calcium supplementation)
- Two-thirds
- Recommendations related to screening (mostly BMD via DXA)
- 76%
- Recommendations related to pharmacological intervention (most commonly bisphosphonates and denosumab)
- 89%
- Recommendations in all three domains
- 54%
Further pooled results
Guideline quality (AGREE II)
- Guidelines rated moderate
- 42
- Guidelines rated high
- 23
- Strong scoring in Scope and Purpose, Clarity of Presentation and Editorial Independence
Original publication
Management of bone health in cancer survivorship: a systematic review of clinical guidelines. Osteoporos Int. Published 24 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →