Osteoporosis & bone health

Association of healthy sleep pattern with the risk of falls and fractures among individuals with cardiovascular disease: a UK Biobank study

Osteoporos IntPublished Prospective cohort study

Authors' conclusion

A healthy sleep pattern is associated with reduced risk of falls and fractures among CVD patients.

Study context

Population
UK Biobank participants with prevalent cardiovascular disease (CVD)median follow-up 13.4 years
Participants
68,961 participants
Exposure
Healthy sleep pattern vs poor sleep pattern
Outcome
Incident falls and fractures
Methodological detailsUK Biobank, Cox regression
  • UK Biobank
  • Cox regression

Main finding

As reported in the abstract

median follow-up 13.4 years
Each group vs poor sleep patternEstimate (95% CI)
Healthy sleep pattern
aHR (fall) 0.79(0.72–0.85)
Healthy sleep pattern
aHR (all fracture) 0.78(0.71–0.86)
Healthy sleep pattern
aHR (hip fracture) 0.79(0.64–0.98)
Events: falls
5565
Events: fractures
4080
Events: hip fractures
833
Lower risk of fall and fracture outcomes per additional healthy sleep factor
8%

Observational data: associations, not effects.

Further findings

Individual sleep factors (7-8 h/day sleep; early chronotype) and fall, all fracture

Hazard ratios (HRs) for sleep 7-8 h/day and early chronotype, ranging between
0.84 and 0.93

Original publication

Association of healthy sleep pattern with the risk of falls and fractures among individuals with cardiovascular disease: a UK Biobank study. Osteoporos Int. Published 23 March 2026. doi:10.1007/s00198-026-07934-6

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