Fibromyalgia & musculoskeletal pain
Social and occupational factors are associated with musculoskeletal pain prevalence in the general population: A population-based cohort study
Authors' conclusion
MP imposes a substantial burden on the French population, particularly among individuals with physically demanding jobs and low education levels.
Study context
- Population
- Adults (18–69 years) representative of the French adult population, baseline data of the CONSTANCES cohortCONSTANCES baseline
- Participants
- 193,436 adults
- Outcome
- Prevalence of MP (Nordic Musculoskeletal Questionnaire; significant pain lasting >30 days in the past 12 months)
- Follow-up
- Past 12 months
Methodological detailspopulation-based, inverse probability weighting, multivariate logistic regression
- Population-based
- Inverse probability weighting
- Multivariate logistic regression
Main finding
As reported in the abstract
MP prevalence
- Pain in at least one anatomical site
- 46.2%
- Low back pain (adjusted prevalence)
- 26.6%
- Shoulder pain
- 21.4%
- Neck pain
- 19.0%
- Knee pain
- 19.1%
Observational data: associations, not effects.
Further findings
Factors associated with low back pain (multivariate logistic regression)
| OR (95% CI) | ||
|---|---|---|
| Female sex | 1.39 (1.32–1.47) | |
| Depression | 1.71 (1.62–1.80) | |
| Comorbidity burden | 1.20 (1.15–1.25) | |
| Moderate occupational physical activity | 1.33 (1.20–1.50) | |
| High occupational physical activity | 1.69 (1.48–1.93) | |
| Very active leisure-time physical activityInversely associated | 0.82 (0.70–0.96) | |
| 0.512Odds ratio (log scale) |
- Older age and obesity associated with low back pain
- Education level but not household income a significant socioeconomic factor associated with musculoskeletal pain (MP)
Original publication
Social and occupational factors are associated with musculoskeletal pain prevalence in the general population: A population-based cohort study. Joint Bone Spine. Published 29 September 2025. doi:10. 1016/ j. jbspin. 2025. 105984
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