Fibromyalgia & musculoskeletal pain

Social and occupational factors are associated with musculoskeletal pain prevalence in the general population: A population-based cohort study

Joint Bone SpinePublished Cross-sectional study

Authors' conclusion

MP imposes a substantial burden on the French population, particularly among individuals with physically demanding jobs and low education levels.

Study context

Population
Adults (18–69 years) representative of the French adult population, baseline data of the CONSTANCES cohortCONSTANCES baseline
Participants
193,436 adults
Outcome
Prevalence of MP (Nordic Musculoskeletal Questionnaire; significant pain lasting >30 days in the past 12 months)
Follow-up
Past 12 months
Methodological detailspopulation-based, inverse probability weighting, multivariate logistic regression
  • Population-based
  • Inverse probability weighting
  • Multivariate logistic regression

Main finding

As reported in the abstract

MP prevalence
Pain in at least one anatomical site
46.2%
Low back pain (adjusted prevalence)
26.6%
Shoulder pain
21.4%
Neck pain
19.0%
Knee pain
19.1%

Observational data: associations, not effects.

Further findings

Factors associated with low back pain (multivariate logistic regression)

OR (95% CI)
Female sex1.39 (1.32–1.47)
Depression1.71 (1.62–1.80)
Comorbidity burden1.20 (1.15–1.25)
Moderate occupational physical activity1.33 (1.20–1.50)
High occupational physical activity1.69 (1.48–1.93)
Very active leisure-time physical activityInversely associated0.82 (0.70–0.96)
Older age and obesity associated with low back pain
Education level but not household income a significant socioeconomic factor associated with musculoskeletal pain (MP)

Original publication

Social and occupational factors are associated with musculoskeletal pain prevalence in the general population: A population-based cohort study. Joint Bone Spine. Published 29 September 2025. doi:10.1016/j.jbspin.2025.105984

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