Sleep disorders in rheumatoid arthritis: Incidence, risk factors and association with dementia
Main finding · Any incident SDResult — go to the resultHazard ratio 1.34 95 % CI 1.11–1.61Authors' conclusion
Individuals with RA (vs non-RA) experienced a significantly increased risk for any SD, particularly insomnia. CVD and CVD risk factors, as well as depression and anxiety increased the risk for incident SD in RA. There was no significant association between SD and dementia in RA.
Study context
- Population
- Residents aged ≥50 years, 8-county region of Minnesota, rheumatoid arthritis (RA) incident 1980–2014 (mean age 65 years, 65% female)matched cohort
- Participants
- 913 vs 913
- Exposure
- RA vs matched non-RA comparators
- RAn = 913
- Non-RAn = 913reference
- Outcome
- Incident sleep disorders (SD)
Methodological detailsmatched 1:1 on age, sex, and calendar year of RA incidence, population-based, 8-county region of Minnesota
- Matched 1:1 on age, sex, and calendar year of RA incidence
- Population-based, 8-county region of Minnesota
Main finding
Any incident SD · median follow-up 10.4 years (RA) and 11.0 years (non-RA)
Hazard ratio
1.34
95 % CI 1.11–1.61
Events by group
RA
234
events
Non-RA
206
events
RAvs Non-RA
HR 1.34 (95 % CI 1.11–1.61)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95 % CI) | |
|---|---|---|
| Incident insomnia | 1.34 (1.03–1.73) | |
| 0.512Hazard ratio (log scale) |
Risk factors for any SD in RA
- Obesity, dyslipidemia, presence of cardiovascular disease (CVD), depression, anxiety, and more recent calendar year of RA incidence were associated with increased risk of any SD in RA
Association of SD with dementia in RA
- No significant association between SD overall and by subtype with dementia in RA
Original publication
Sleep disorders in rheumatoid arthritis: Incidence, risk factors and association with dementia. Semin Arthritis Rheum. Published 11 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →