Vasculitis & polymyalgia rheumatica
Sleep and circadian parameters in Behçet’s syndrome: a comparative analysis using actigraphy and questionnaires
Authors' conclusion
Active disease and fibromyalgia are associated with sleep and circadian rhythm disturbances in BS patients.
Study context
- Population
- BD patients (45) and matched healthy controls (HCs)45 Behçet syndrome (BS) patients · 61 HCs
- Exposure
- BD patients, with or without active disease and comorbid FM, vs HCs
- HCsn = 61reference
- Outcome
- Sleep and circadian parameters (actigraphy; Pittsburgh Sleep Quality Index; reduced Morningness-Eveningness Questionnaire)
Methodological detailsage-, BMI-, sex- and smoking habits-matched, actigraphy and questionnaires, linear regression models
- Age-, BMI-, sex- and smoking habits-matched
- Actigraphy and questionnaires
- Linear regression models
Main finding
As reported in the abstract
Sleep and circadian parameters
- BS with active disease and/or FM: significantly lower sleep quality, significantly higher sleep fragmentation and a tendence towards less robust circadian rhythms vs other participants
- BS without active disease or FM did not significantly differ from HCs in sleep and circadian parameters
Observational data: associations, not effects.
Further findings
Actigraphically-determined obstructive sleep apnoea syndrome (OSAS) risk
- Higher in all BS patients vs HCs
Original publication
Sleep and circadian parameters in Behçet’s syndrome: a comparative analysis using actigraphy and questionnaires. Rheumatology (Oxford). Published 9 June 2025. doi:10. 1093/ rheumatology/ keaf326
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