Vasculitis & polymyalgia rheumatica
Behçet's disease beyond the criteria: insights from a tertiary centre in Turkey
Authors' conclusion
According to various classification criteria, 15-40% of patients with BD do not meet established classification criteria at any point during follow-up, yet significant organ involvement remains prevalent.
Study context
- Population
- Adults with clinically diagnosed Behçet's disease (BD), Hacettepe University Vasculitis Research Centre database, Turkey49.8% males
- Participants
- 804 adults
- Exposure
- Fulfilment of International Study Group (ISG) vs International Criteria for Behçet's Disease (ICBD) classification criteria in clinically diagnosed BD
- Outcome
- Fulfilment of ISG and ICBD criteria
- Follow-up
- At diagnosis and during
Methodological detailssingle-centre, tertiary centre, Physician's clinical judgment as gold standard for diagnosis, Paediatric cases and incomplete clinical data excluded
- Single-centre
- Tertiary centre
- Physician's clinical judgment as gold standard for diagnosis
- Paediatric cases and incomplete clinical data excluded
Main finding
As reported in the abstract
Patients fulfilling classification criteria · at diagnosis
Observational data: associations, not effects.
Further findings
- Criteria fulfilment during follow-up — ICBD
- 84.7%
- Significant organ involvement (ocular, vascular or neurological) in patients not meeting the criteria — ICBD
- 30.9%
- Use of ≥1 immunosuppressive agent in patients not meeting the criteria — ICBD
- 38.2%
- Criteria fulfilment during follow-up: ISG 59.0%
- Significant organ involvement (ocular, vascular or neurological) in patients not meeting the criteria: ISG 47.9%
- Use of ≥1 immunosuppressive agent in patients not meeting the criteria: ISG 48.5%
Original publication
Behçet's disease beyond the criteria: insights from a tertiary centre in Turkey. Clin Exp Rheumatol. Published 9 June 2025. doi:10.
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