Similar myocardial infarction characteristics and short-term outcomes in patients with and without inflammatory joint diseases: A nationwide Norwegian study
Authors' conclusion
RA, axSpA and PsA patients showed comparable MI presentations, disease courses and short-term outcomes to those without IJD.
Study context
- Population
- Adults in Norway with a first myocardial infarction (MI), Norwegian MI register, January 2013–December 2017, without known atherosclerotic CVD
- Participants
- 981 / 314 / 434 / 34,783
- Exposure
- RA, axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) vs no inflammatory joint disease, in patients with first MI
- RAn = 981
- axSpAn = 314
- PsAn = 434
- non-IJDn = 34,783reference
- Outcome
- MI presentation, myocardial damage, acute treatment, in-hospital adverse events, short-term outcomes and secondary cardio-preventive drugs
Methodological detailsage-adjusted models stratified by sex, logistic regression and generalized linear models
- Age-adjusted models stratified by sex
- Logistic regression and generalized linear models
Main finding
As reported in the abstract
- Chest pain was the most common symptom in all groups; no indication that inflammatory joint diseases (IJD) subgroups had atypical presentations more often than non-IJD
- Myocardial damage indicators (STEMI rates, troponin T levels, multi-vessel disease) not worse in IJD
- Acute treatments equally, or more, often performed in IJD vs non-IJD
- None of the secondary cardio-preventive drugs prescribed less frequently to IJD than non-IJD
Observational data: associations, not effects.
Safety
In-hospital adverse events and short-term mortality
- All similar or less common in the IJD subgroups vs non-IJD
Original publication
Similar myocardial infarction characteristics and short-term outcomes in patients with and without inflammatory joint diseases: A nationwide Norwegian study. Semin Arthritis Rheum. Published 27 May 2025. doi:10.
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