Across rheumatic diseases

Evaluating the reliability of cardiovascular risk scales in patients with chronic inflammatory rheumatic diseases

Semin Arthritis RheumPublished Prospective cohort study

Authors' conclusion

The higher correlation and reliability observed between SCORE2, PREVENT-CVD, and PREVENT-ASCVD in our series of CIRD patients followed over a 10-year period suggest that these scales may be largely interchangeable for identifying high-risk CIRD patients.

Study context

Population
Patients with chronic inflammatory rheumatic diseases (RA, AS, PsA) from 67 hospitals across Spain (CARdiovascular in RheuMAtology (CARMA) project), recruited July 2010–January 2012, 10-year follow-up
Participants
2,080 patients
Exposure
QRISK3 vs SCORE2 vs PREVENT-CVD vs PREVENT-ASCVD 10-year cardiovascular disease (CVD) risk scores
Outcome
Predicted 10-year CV events, average across cohort
Follow-up
10 years
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

QRISK3 and PREVENT-CVD predicted an average of ≈10% CV events

10 %

SCORE2 and PREVENT-ASCVD predicted an average of only 6.3%

6.3 %

Linear correlation coefficients between each pair of scales consistently above 0.8; average

0.9074

Observational data: associations, not effects.

Original publication

Evaluating the reliability of cardiovascular risk scales in patients with chronic inflammatory rheumatic diseases. Semin Arthritis Rheum. Published 24 February 2025. doi:10.1016/j.semarthrit.2025.152694

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