Across rheumatic diseases

Male patients with inflammatory joint diseases are less likely than controls to be childless: results from a Norwegian population-based cohort study of 10 865 patients

Ann Rheum DisPublished Retrospective cohort study

Authors' conclusion

In this large cohort study we found that patients with IJD have a higher number of children and are less likely to be childless compared with controls.

Study context

Population
Men with inflammatory joint diseases in the Norwegian Arthritis Registry and matched men from the general population, Norwaymatched cohort
Participants
10,865 vs 54,325
Exposure
Men with inflammatory joint diseases (IJDs) vs matched men without IJDs from the general population
  • IJDn = 10,865
  • Controlsn = 54,325reference
Outcome
Number of children per man and proportion of childless men (proxy of fertility)
Methodological detailsnationwide, population-based, matched 1:5 on birth year and county of residence
  • Nationwide
  • Population-based
  • Matched 1:5 on birth year and county of residence

Main finding

As reported in the abstract

Mean number of children per man
  • IJD vs Controls: P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeP value
Childless menP < 0.001
Childlessness in men diagnosed after year 2000 at 30-39 years of age (subgroup)P < 0.001

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Male patients with inflammatory joint diseases are less likely than controls to be childless: results from a Norwegian population-based cohort study of 10 865 patients. Ann Rheum Dis. Published 12 March 2024. doi:10.1136/ard-2023-224998

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