Vasculitis & polymyalgia rheumatica
Significance of HLA-B[*]51 allele expression in Crohn's disease: a case-control study
Main finding · HLA-B*51 allele positivityResult — go to the resultOdds ratio 0.238 95% CI 0.089–0.637Authors' conclusion
Our finding suggests that determination of HLA-B*51 allele status may contribute to the differential diagnosis between CD and BD.
Study context
- Population
- Argentine patients with confirmed Crohn's disease, compared with a previous Argentine Behçet's disease (BD) cohort
- Participants
- 70 vs 34
- Comparison
- HLA-B*51 status in crohn's disease (CD) vs previous BD cohort
- CDn = 70
- BDn = 34reference
- Outcome
- HLA-B*51 allele positivity
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Odds ratio
0.238
95% CI 0.089–0.637
P = 0.004
By group
CDvs BD
OR 0.238 (95% CI 0.089–0.637); P = 0.004
Observational data: associations, not effects.
Original publication
Significance of HLA-B[*]51 allele expression in Crohn's disease: a case-control study. Clin Exp Rheumatol. Published 24 November 2022. doi:10.
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