Shoulder injection of platelet-rich plasma versus corticosteroids in rotator cuff tendinopathies

Scand J RheumatolPublished Randomised controlled trial

Authors' conclusion

Corticosteroids were more effective for pain reduction at 3 months, while PRP provided equivalent functional improvement.

Study context

Population
Chronic, non-ruptured rotator cuff tendinopathies (mean age 62.3 ± 8.3 years; 84.6% female)
Participants
52 participants
Comparison
Corticosteroid vs platelet-rich plasma (PRP) shoulder injection
  • Corticosteroidn = 26
  • PRPn = 26
Methodological detailsprospective
  • Prospective

Primary result

As reported in the abstract

Pain reduction (ΔVAS) · 3 months

Corticosteroid

3.35

PRP

1.75

P = 0.02

Further findings

OutcomeP value
Pain reduction · 1 weekP = 0.49

Pain reduction · 1 week

Comparable between groups

Function (QuickDASH, Shoulder Pain and Disability Index (SPADI))

Similar between groups; non-significant trend favouring corticosteroids for QuickDASH, not confirmed by multivariate analysis

Safety

Post-injection pain · mild and transient

Local oedema · mild and transient

Original publication

Shoulder injection of platelet-rich plasma versus corticosteroids in rotator cuff tendinopathies. Scand J Rheumatol. Published 18 March 2026. doi:10.1080/03009742.2026.2620888

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