Sex and menopausal status differences in coronary calcification and extra-coronary computed tomography findings in inflammatory arthritis
Main finding · CAC ≥100Result — go to the resultOdds ratio 0.29 95% CI 0.17–0.49Authors' conclusion
Sex and menopausal status are associated with coronary and extra-coronary CT abnormalities in IA patients.
Study context
- Population
- Inflammatory arthritis (IA) patients aged >40 years without prior CVD31% male, 14% pre-, 55% post-menopausal
- Participants
- 597 patients
- Exposure
- Males vs pre-menopausal females vs post-menopausal females with IA
- Outcome
- CAC score by the Agatston method (0, 1-99, ≥100)
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Main finding
CAC ≥100
Odds ratio
0.29
95% CI 0.17–0.49
By group
Post-menopausal femalesvs Males
OR 0.29 (95% CI 0.17–0.49)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Aortic calcification and aortic enlargement
- Aortic calcification in post-menopausal females (more)
- 44%
- Aortic enlargement in post-menopausal females (more)
- 23%
- P value (both)
- all p≤0.001
- Post-menopausal associations with aortic changes not significant after adjustment
Left main, circumflex and right coronary calcification
- More in males
- P ≤ 0.001
Original publication
Sex and menopausal status differences in coronary calcification and extra-coronary computed tomography findings in inflammatory arthritis. Clin Exp Rheumatol. Published 10 March 2026. doi:10.
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