Gout & crystal arthritis

Serum Urate Monitoring Among Older Adults With Gout: Initiating Urate‐Lowering Therapy in Ontario, Canada

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

SUA testing is suboptimal among older adults with gout initiating ULT but is improving over time. ULT prescriber, patient, and prescription characteristics were correlated with SUA testing.

Study context

Population
Patients aged ≥66 years with gout newly dispensed urate-lowering therapy (ULT) between 2010 and 2019, Ontario, Canada
Participants
44,438 patients
Outcome
SUA testing after ULT initiation; factors associated with SUA monitoring
Follow-up
6 months
Methodological detailspopulation-based, multilevel logistic regression clustered by ULT prescriber
  • Population-based
  • Multilevel logistic regression clustered by ULT prescriber

Main finding

As reported in the abstract

Factors associated with SUA monitoring within 6 months (vs rheumatologists for prescriber specialty)
Odds ratio (95% CI)
Family physiciansvs Rheumatologists
0.26(0.23–0.29)
Internistsvs Rheumatologists
0.34(0.29–0.39)
Nephrologistsvs Rheumatologists
0.37(0.30–0.45)
Other specialtiesvs Rheumatologists
0.25(0.21–0.29)
Male physicians
0.87(0.83–0.91)
Rural residence
0.81(0.77–0.86)
Lower socioeconomic status
0.91(0.85–0.97)
Coprescription of colchicine/oral corticosteroids
1.31(1.23–1.40)
Serum urate (SUA) testing at 6 months in 2010
56.4%
SUA testing in 2019 (rose over time)
71.3%
Trend over time
P < 0.0001

Observational data: associations, not effects.

Original publication

Serum Urate Monitoring Among Older Adults With Gout: Initiating Urate‐Lowering Therapy in Ontario, Canada. Arthritis Care Res (Hoboken). Published 26 June 2023. doi:10.1002/acr.25167

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