Lupus & antiphospholipid syndrome
Seroprevalence of Toxoplasma gondii immunoglobulins and its association with systemic lupus erythematosus: A systematic review and meta-analysis
Pooled result · T. gondii IgG seropositivityResult — go to the resultRelative risk 2.14 95% CI 1.42–3.22Authors' conclusion
In summary, this study suggests that T. gondii IgG is more prevalent in patients with SLE than in healthy individuals in areas where T. gondii infections are more frequent.
Study context
- Population
- Published studies of T. gondii antibodies in patients with systemic lupus erythematosus (SLE) and controls11 studies
- Comparison
- SLE vs healthy controls
- Outcome
- Association between T. gondii seropositivity and SLE
Pooled result
T. gondii IgG seropositivity
Relative risk
2.14
95% CI 1.42–3.22
P = 0.000
SLEvs Healthy controls
RR 2.14 (95% CI 1.42–3.22); P = 0.000
As reported in the abstract
Further pooled results
T. gondii IgM seropositivity
- Comparable between patients with SLE and healthy controls
Prevalence of anti-T. gondii antibodies in SLE
- IgG prevalence
- 33.9%
- IgM prevalence
- 7.7%
Original publication
Seroprevalence of Toxoplasma gondii immunoglobulins and its association with systemic lupus erythematosus: A systematic review and meta-analysis. Lupus. Published 11 August 2024. doi:10. 1177/ 09612033241273048
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